Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenepropanoic acid, 4-hydroxy-, methyl ester → 3-[4-(2-Isopropylsulfanyl-5-methyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenepropanoic acid, 4-hydroxy-, methyl ester | HCID 79706 | — |
| 반응물 | 3-Chloromethyl-2-isopropylsulfanyl-5-methyl-pyridine | HCID 90118277 | — |
| 생성물 | 3-[4-(2-Isopropylsulfanyl-5-methyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid | HCID 74222199 | 55% |
반응 단계
3-Chloromethyl-2-isopropylsulfanyl-5-methyl-pyridine (0.052 g, 0.24 mmol) obtained in Step D of Preparation Example 30 and 3-(4-hydroxy-phenyl)-propionic acid methyl ester (0.043 g, 0.24 mol) obtained in Preparation Example 4 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (55%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447044B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-4a89aa6084f246eeb05445ac6e85f153 |
| 출처 메모 | uspto-grants-2016_09 |