N,N-Dimethylethylenediamine → HCID 71542099, 화합물

HRID 629523노트

반응식

HRID 629523 반응식
[C:1]12([C:11]3[CH:21]=[CH:20][C:14]([O:15][CH2:16][C:17](O)=[O:18])=[C:13]([CH3:22])[CH:12]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:23][N:24]([CH3:28])[CH2:25][CH2:26][NH2:27]>>[C:1]12([C:11]3[CH:21]=[CH:20][C:14]([O:15][CH2:16][C:17]([NH:27][CH2:26][CH2:25][N:24]([CH3:28])[CH3:23])=[O:18])=[C:13]([CH3:22])[CH:12]=3)[CH2:10][CH:5]3[CH2:4][CH:3]([CH2:9][CH:7]([CH2:6]3)[CH2:8]1)[CH2:2]2

참가 물질

3

반응물 2

HCID 66053N,N-DimethylethylenediamineHCID 86729431HCID 86729431, 화합물

생성물 1

HCID 71542099HCID 71542099, 화합물수율 90%

실험 절차

The title compound was prepared from 2-(4-(adamantan-1-yl)-2-methylphenoxy)acetic acid (0.2 g, 0.66 mmol), prepared from the step 4 of the example 5, and N,N-dimethylethane-1,2-diamine (0.058 g, 0.66 mmol) according to the example 1, which was given 2-(4-(adamantan-1-yl)-2-methylphenoxy)-N-(2-(dimethylamino)ethyl)acetamide as a white solid (0.22 g, 89.4% yield).

출처 및 근거

ORD 기록
ord-28b0e01970894219bb0543e49da55263
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09315507B2

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