6-Nitro-2,3-dihydrobenzofuran-5-amine → 2,3-Dihydrobenzofuran-5,6-diamine
반응식
[NH2:1][C:2]1[C:3]([N+:11]([O-])=O)=[CH:4][C:5]2[O:9][CH2:8][CH2:7][C:6]=2[CH:10]=1.[H][H]>CCO.[Pd]>[NH2:1][C:2]1[C:3]([NH2:11])=[CH:4][C:5]2[O:9][CH2:8][CH2:7][C:6]=2[CH:10]=1참가 물질
5
실험 절차
The product obtained in Step 5 (2.5 g, 13.9 mmol) and Pd/C (0.5 g) were dissolved in EtOH (50 mL), hydrogenated in a Parr hydrogenation apparatus at room temperature and a hydrogen pressure of 50 PSI for 12 h. The catalyst was removed by filtration, the ethanol solution of the product was directly used in the next step of reaction.
후처리
- customThe catalyst was removed by filtration
- customthe ethanol solution of the product was directly used in the next step of reaction
출처 및 근거
- ORD 기록
- ord-02a7d3eeb73a4c6fbc41806e5940cffe
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09315513B2
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