참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Naphthoic acid | HCID 7123 | — |
| 반응물 | 2,4-Diaminophenol hydrochloride | HCID 8715 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 2-Naphthalen-2-yl-benzooxazol-5-yl-amine | HCID 736012 | 75% |
반응 단계
80 μmol of 2,4-diaminophenol.2HCl and 80 μmol of naphthalene-2-carboxylic acid were dissolved in 100 mg of PPA, and then, the mixed solution was stirred at a temperature of 180° C. for 3 to 4 hours. After completion of the reaction, the reaction solution was cooled, neutralized with 10% NaOH, and filtered by using distilled water for recrystallization in a slow manner, thereby obtaining 15.6 mg of 2-(naphthalene-2-yl)benzo[d]oxazole-5-amine (Derivative #3) (yield: 75%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09447054B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_09 |
|---|
| ORD ID | ord-bf87e7cb139f4e8ea7b4af588f1a563f |
|---|
| 출처 메모 | uspto-grants-2016_09 |
|---|
