Methyl 3-bromoisonicotinate → HCID 83335881, 화합물

HRID 63037

반응식

HRID 63037 반응식
Cl.[NH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:7]([C:8]#[N:9])=[CH:6][CH:5]=1.Br[C:13]1[CH:22]=[N:21][CH:20]=[CH:19][C:14]=1[C:15]([O:17][CH3:18])=[O:16]>>[C:8]([C:7]1[CH:10]=[CH:11][C:4]([CH2:3][NH:2][C:19]2[CH:20]=[N:21][CH:22]=[CH:13][C:14]=2[C:15]([O:17][CH3:18])=[O:16])=[CH:5][CH:6]=1)#[N:9]

참가 물질

3

반응물 2

HCID 2762700Methyl 3-bromoisonicotinateHCID 99422504-(Aminomethyl)benzonitrile hydrochloride

생성물 1

HCID 83335881HCID 83335881, 화합물수율 4%

실험 절차

The title compound was prepared in 4% yield from 4-(aminomethyl)-benzonitrile hydrochloride and methyl 3-bromoisonicotinate according to the procedure for Preparation 4A. 1H NMR (500 MHz, CDCl3): δ 8.07 (s, 1H), 7.97 (d, 2H, J=5.0 Hz), 7.63-7.70 (m, 3H), 7.46 (d, 2H, J=8.3 Hz), 4.61 (d, 2H, J=6.1 Hz), 3.94 (s, 3H). [M+H] calc'd for C15H13N3O2, 268. found 268.

출처 및 근거

ORD 기록
ord-0cd2980b2385491d90d66561ce8be405
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09447045B2

연결된 노트

불러오는 중…