Methyl 4-Amino-3-chlorobenzoate → (4-Amino-3-chlorophenyl)methanol
반응식
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6](OC)=[O:7])=[CH:4][C:3]=1[Cl:12].[H-].[Al+3].[Li+].[H-].[H-].[H-].NC1C(Cl)=CC(CO)=C(OC)C=1>O1CCCC1>[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([CH2:6][OH:7])=[CH:4][C:3]=1[Cl:12]참가 물질
5
실험 절차
Obtained as a light brown solid (76%) starting from commercially available methyl 4-amino-3-chlorobenzoate (4 g; 0.021 mol) and lithium aluminium hydride (1.09 g; 0.028 mol) in 144 ml tetrahydrofuran following the experimental procedure as described for intermediate 38.
출처 및 근거
- ORD 기록
- ord-3ac020c2dd284d98b86967f778435863
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09315463B2
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