Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Dichlorobenzylamine → 3-[(2,4-Dichlorobenzyl)amino]pyridine-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Dichlorobenzylamine | HCID 1485 | — |
| 반응물 | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| 생성물 | 3-[(2,4-Dichlorobenzyl)amino]pyridine-4-carboxylic acid | HCID 86728205 | 42% |
반응 단계
The title compound was prepared in 42% yield from 2,4-dichlorobenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.49 (br s, 1H), 8.04 (s, 1H), 7.87 (d, 1H, J=5.0 Hz), 7.66 (s, 1H), 7.59 (d, 1H, J=5.0 Hz), 7.38-7.42 (m, 2H), 4.63 (s, 2H). [M+H] calc'd for C13H10Cl2N2O2, 297, 299. found 297, 299.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447045B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-d43b8df6647c4dd6959c42c6f51f1f0a |
| 출처 메모 | uspto-grants-2016_09 |