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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 630527생성일: 2026년 10월 27일

2-Bromo-4-chloropyridine → (1-(5-(4-Chloropyridin-2-yl)pyrimidin-2-yl)-3-(methylsulfinyl)-1H-indol-6-yl)(morpholino)methanone

https://huagongshe.com/reaction/630527

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-4-chloropyridineHCID 2762836—
반응물(1-(5-Bromopyrimidin-2-yl)-3-(methylsulfinyl)-1H-indol-6-yl)(morpholino)methanoneHCID 118666026—
반응물(1-(5-(4-(2-Hydroxypropan-2-yl)pyridin-2-yl)pyrimidin-2-yl)-3-(methylthio)-1H-indol-6-yl)(morpholino)methanoneHCID 118666145—
생성물(1-(5-(4-Chloropyridin-2-yl)pyrimidin-2-yl)-3-(methylsulfinyl)-1H-indol-6-yl)(morpholino)methanoneHCID 118666088—

반응 단계

Prepared from (1-(5-bromopyrimidin-2-yl)-3-(methylsulfinyl)-1H-indol-6-yl)(morpholino)-methanone (0.5 g, 1.11 mmol) and 2-bromo-4-chloropyridine (0.23 g, 1.22 mmol) analogously to the experimental procedure for 289a). White solid. Yield: 61 mg (11% of theory)

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09315490B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-88aa0a80d8324aa69676cab35d892fd5
출처 메모uspto-grants-2016_04