2-Bromobenzylamine → 3-[(2-Bromobenzyl)amino]pyridine-4-carboxylic acid

HRID 63053

반응식

HRID 63053 반응식
[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH2:5].F[C:11]1[CH:19]=[N:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14]>>[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH:5][C:16]1[CH:17]=[N:18][CH:19]=[CH:11][C:12]=1[C:13]([OH:15])=[O:14]

참가 물질

3

반응물 2

HCID 3340722-BromobenzylamineHCID 3453613-Fluoropyridine-4-carboxylic acid

생성물 1

HCID 817503783-[(2-Bromobenzyl)amino]pyridine-4-carboxylic acid수율 33%

실험 절차

The title compound was prepared in 33% yield from 2-bromobenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. [M+H] calc'd for C13H11BrN2O2, 307, 309. found 307, 309.

출처 및 근거

ORD 기록
ord-ca170d50901449aaa052a58a30a1b9d9
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09447045B2

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