Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Aminomethyl)aniline → 3-[(2-Aminobenzyl)amino]pyridine-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Aminomethyl)aniline | HCID 178096 | — |
| 반응물 | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| 생성물 | 3-[(2-Aminobenzyl)amino]pyridine-4-carboxylic acid | HCID 77105910 | 9% |
반응 단계
The title compound was prepared in 9% yield from 2-aminobenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 8.16 (s, 1H), 7.82 (d, 1H, J=5.0 Hz), 7.56 (d, 1H, J=5.0 Hz), 7.05 (d, 1H, J=7.5 Hz), 6.97 (td, 1H, J=7.8, 1.4 Hz), 6.66 (d, 1H, J=7.9 Hz), 6.52 (td, 1H, J=7.4, 1.0 Hz), 4.35 (s, 2H). [M+H] calc'd for C13H13N3O2, 244. found 244.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447045B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-a6c8efd0809845a2a9fc11e3939ca554 |
| 출처 메모 | uspto-grants-2016_09 |