Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Trifluoromethyl)benzylamine → 3-{[3-(Trifluoromethyl)benzyl]amino}pyridine-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Trifluoromethyl)benzylamine | HCID 75962 | — |
| 반응물 | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| 생성물 | 3-{[3-(Trifluoromethyl)benzyl]amino}pyridine-4-carboxylic acid | HCID 77106114 | 39% |
반응 단계
The title compound was prepared in 39% yield from 3-trifluoromethyl-benzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.47 (br s, 1H), 8.12 (s, 1H), 7.83 (d, 1H, J=5.0 Hz), 7.74 (s, 1H), 7.57-7.69 (m, 4H), 4.67 (s, 2H). [M+H] calc'd for C14H11F3N2O2, 297. found 297.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447045B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-5246ac3e9aae48f0b1ba438aaa3cf5c3 |
| 출처 메모 | uspto-grants-2016_09 |