Nitromethane → 4-nitro-1,3-diphenylbutan-1-one
반응식
[CH:1](=[CH:8][C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:17]([CH3:20])([O-:19])=[O:18].C(NCC)C>CO>[N+:17]([CH2:20][CH:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:8][C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10])([O-:19])=[O:18]참가 물질
5
실험 절차
In a 1 L flask, 94.7 g (0.455 mol) of benzylideneacetophenone were dissolved in 600 g of methanol, admixed with 138.9 g (2.275 mol) of nitromethane and 166.4 g (2.275 mol) of diethylamine and refluxed for 16 h. The solvent was half distilled off in vacuo and the precipitated solid was separated off and dried to constant weight in vacuo to obtain 118 g (438 mmol) of 4-nitro-1,3-diphenylbutan-1-one.
후처리
- temperaturerefluxed for 16 h
- distillationdistilled off in vacuo
- customthe precipitated solid was separated off
- customdried to constant weight in vacuo
출처 및 근거
- ORD 기록
- ord-b37301f462d643e39a5b4a56c75d255a
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09317012B2
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