Phenyl chloroformate → phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate

HRID 631687노트

반응식

HRID 631687 반응식
Cl.[C:2]([C:6]1[CH:10]=[C:9]([NH2:11])[N:8]([CH2:12][CH:13]([CH3:15])[CH3:14])[N:7]=1)([CH3:5])([CH3:4])[CH3:3].Cl[C:17]([O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:18]>>[C:2]([C:6]1[CH:10]=[C:9]([NH:11][C:17](=[O:18])[O:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:8]([CH2:12][CH:13]([CH3:15])[CH3:14])[N:7]=1)([CH3:5])([CH3:4])[CH3:3]

참가 물질

3

반응물 2

HCID 15891Phenyl chloroformateHCID 668762943-tert-butyl-1-isobutyl-1H-pyrazol-5-amine hydrochloride

생성물 1

HCID 66876741phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate

실험 절차

Following the procedure described for Example 330A Step 2, reaction of 3-tert-butyl-1-isobutyl-1H-pyrazol-5-amine hydrochloride with phenyl chloroformate, afforded phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate which was used in the subsequent step.

출처 및 근거

ORD 기록
ord-cfafa94659e7479ead69e086d7e55832
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09320739B2

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