Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentanenitrile, 4,4-dimethyl-3-oxo- → HCID 66876507, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentanenitrile, 4,4-dimethyl-3-oxo- | HCID 108871 | — |
| 반응물 | 4-(Trifluoromethyl)phenylhydrazine | HCID 136200 | — |
| 생성물 | HCID 66876507 | HCID 66876507 | 60.1% |
반응 단계
The title compound was prepared from 4-(trifluoromethyl)-phenylhydrazine (1.41 g, 8.0 mmol) and 4,4-dimethyl-3-oxopentanenitrile (1.0 g, 8.0 mmol) using the procedure in Example 161A Step 3 to give to give 3-tert-butyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine (1.36 g, 4.81 mmol, 60%). 1H NMR (300 MHz, DMSO-d6) δ 7.81 (d, 2H), 7.80 (d, 2H), 5.44 (s, 3H), 1.22 (s, 9H); LC-MS (ESI) m/z 284 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09320739B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-02d5a31b4afb4125ac5d9ab27c2410b3 |
| 출처 메모 | uspto-grants-2016_04 |