6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid → HCID 71093511, 화합물

HRID 632115노트

반응식

HRID 632115 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][C:9]=2[CH:17]2[CH2:19][CH2:18]2)[CH:5]=[CH:6][CH:7]=1.[CH3:20][C:21]([CH3:28])([C:23]1[O:24][CH:25]=[CH:26][N:27]=1)[NH2:22]>>[CH3:20][C:21]([NH:22][C:14]([C:12]1[CH:11]=[CH:10][C:9]([CH:17]2[CH2:19][CH2:18]2)=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:23]1[O:24][CH:25]=[CH:26][N:27]=1)[CH3:28]

참가 물질

3

반응물 2

HCID 710874536-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acidHCID 82418817alpha,alpha-Dimethyl-2-oxazolemethanamine

생성물 1

HCID 71093511HCID 71093511, 화합물

실험 절차

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (Example 48 e) and α,α-dimethyl-2-oxazolemethanamine (CAN 1211519-76-4) as starting materials, MS (EI): m/e=382.1 [M+H]+.

출처 및 근거

ORD 기록
ord-5805339042444df7b4da81298b356026
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321727B2

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