2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → HCID 71093619, 화합물

HRID 632116

반응식

HRID 632116 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][C:9]=2[CH:17]2[CH2:19][CH2:18]2)[CH:5]=[CH:6][CH:7]=1.[CH3:20][C:21]([CH3:29])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[NH2:22]>>[CH3:20][C:21]([NH:22][C:14]([C:12]1[CH:11]=[CH:10][C:9]([CH:17]2[CH2:19][CH2:18]2)=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[CH3:29]

참가 물질

3

반응물 2

HCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 710874536-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid

생성물 1

HCID 71093619HCID 71093619, 화합물

실험 절차

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (Example 48 e) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (EI): m/e=397.1 [M+H]+.

출처 및 근거

ORD 기록
ord-69310715d85f43ceb38882f543343b8b
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321727B2

연결된 노트

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