(S)-alpha-amino-cyclopropanepropanamide → HCID 71105590, 화합물

HRID 632118노트

반응식

HRID 632118 반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[NH2:18][C@@H:19]([CH2:23][CH:24]1[CH2:26][CH2:25]1)[C:20]([NH2:22])=[O:21]>>[C:20]([C@@H:19]([NH:18][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])[CH2:23][CH:24]1[CH2:26][CH2:25]1)(=[O:21])[NH2:22]

참가 물질

3

반응물 2

HCID 53964035(S)-alpha-amino-cyclopropanepropanamideHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

생성물 1

HCID 71105590HCID 71105590, 화합물

실험 절차

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and (S)-2-amino-3-cyclopropyl-propanamide (CAN 156077-93-9) as starting materials, MS (LC/MS): m/e=344.3 [M+H]+.

출처 및 근거

ORD 기록
ord-723ced28c79c47fdae71129ac23cc65a
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321727B2

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