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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 632198생성일: 2026년 10월 26일

1-(2-Amino-2-methylpropoxy)-2-methoxyethane → 6-(3-Chloro-phenyl)-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [2-(2-methoxy-ethoxy)-1,1-dimethyl-ethyl]-amide

https://huagongshe.com/reaction/632198

반응식

참여 물질

역할이름HCID투입량
반응물1-(2-Amino-2-methylpropoxy)-2-methoxyethaneHCID 64537168—
반응물6-(3-Chloro-phenyl)-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acidHCID 71087673—
생성물6-(3-Chloro-phenyl)-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [2-(2-methoxy-ethoxy)-1,1-dimethyl-ethyl]-amideHCID 71105628—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 140 a) and 2-(2-methoxy-ethoxy)-1,1-dimethyl-ethylamine (CAN 947723-29-7) as starting materials, MS (EI): m/e=454.1 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09321727B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-98dc535223ab47f6865d789681853a51
출처 메모uspto-grants-2016_04