반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[NH2:18][C:19]([CH3:23])([CH3:22])[C:20]#[N:21]>>[C:20]([C:19]([NH:18][C:15](=[O:17])[C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)([CH3:23])[CH3:22])#[N:21]참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-amino-2-methyl-propanenitrile, (CAN 19355-69-2) as starting materials, LC-MS (UV peak area/ESI) 89%, 300.1702 (M+H)+.
출처 및 근거
- ORD 기록
- ord-8d965839968948339ac0b1fb55129f19
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09321727B2
연결된 노트
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