반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.Cl.[CH2:19]([O:21][C:22](=[O:29])[C:23]([NH2:28])([CH2:26][CH3:27])[CH2:24][CH3:25])C>>[CH3:19][O:21][C:22](=[O:29])[C:23]([NH:28][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])([CH2:26][CH3:27])[CH2:24][CH3:25]참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and 2-amino-2-ethyl-butanoic acid ethyl ester hydrochloride (1:1) (CAN 70974-26-4) as starting materials, LC-MS (UV peak area/ESI) 100%, 361.2120 (M+H)+.
출처 및 근거
- ORD 기록
- ord-c04b3ee413754373ac816bccf2990673
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09321727B2
연결된 노트
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