2-amino-N,N-dimethyl-2-phenylacetamide hydrochloride → HCID 71105675, 화합물
반응식
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[N:15]2[CH2:18][C:17]([F:20])([F:19])[CH2:16]2)[CH2:3][CH2:2]1.Cl.[NH2:22][CH:23]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[C:24]([N:26]([CH3:28])[CH3:27])=[O:25]>>[CH3:27][N:26]([CH3:28])[C:24]([CH:23]([NH:22][C:12]([C:10]1[CH:9]=[CH:8][C:7]([N:15]2[CH2:18][C:17]([F:20])([F:19])[CH2:16]2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)=[O:25]참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 69 b) and 2-amino-N,N-dimethyl-2-phenylacetamide hydrochloride (CAN 1214036-19-7) as starting materials. MS (EI): m/e=445.1 [M+H]+.
출처 및 근거
- ORD 기록
- ord-271d4afaefde4733b65d38e03fb2db4c
- 출처 데이터셋
- uspto-grants-2016_04