2-AMino-4-Methylpentanenitrile Hydrochloride → HCID 71105682, 화합물
반응식
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[N:15]2[CH2:18][C:17]([F:20])([F:19])[CH2:16]2)[CH2:3][CH2:2]1.Cl.[NH2:22][CH:23]([CH2:26][CH:27]([CH3:29])[CH3:28])[C:24]#[N:25]>>[C:24]([CH:23]([NH:22][C:12]([C:10]1[CH:9]=[CH:8][C:7]([N:15]2[CH2:18][C:17]([F:20])([F:19])[CH2:16]2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])[CH2:26][CH:27]([CH3:29])[CH3:28])#[N:25]참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 69 b) and 2-amino-4-methylpentanenitrile hydrochloride (CAN 72177-82-3) as starting materials. MS (EI): m/e=379.1 [M+H]+.
출처 및 근거
- ORD 기록
- ord-05c31e8832b54e198a19cdaf664ba5ef
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09321727B2