Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-[(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-[(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid ethyl ester | HCID 71087768 | — |
| 생성물 | 2-[(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid | HCID 71087550 | — |
반응 단계
In analogy to the procedure described in Example 252 b, 2-[(6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid ethyl ester (Example 289) was treated with sodium hydroxide to give the title compound as colorless oil. MS: 376.3 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09321727B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-6171b95102fe409daa413cee2cac361f |
| 출처 메모 | uspto-grants-2016_04 |