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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 632362생성일: 2026년 10월 26일

2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amine → 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2,2,2-trifluoro-1-pyridin-2-yl-ethyl)-amide

https://huagongshe.com/reaction/632362

반응식

참여 물질

역할이름HCID투입량
반응물2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amineHCID 25219911—
반응물5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 71087649—
생성물5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2,2,2-trifluoro-1-pyridin-2-yl-ethyl)-amideHCID 86674790—

반응 단계

The title compound was synthesized in analogy to Example 280c, using 5-cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 301a) and 2,2,2-trifluoro-1-(pyridin-2-yl)ethanamine (CAN 35272-15-2) as starting materials, MS (EI): m/e=420.1 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09321727B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-d81a211e5e3549528c5c9bf9b43865a0
출처 메모uspto-grants-2016_04