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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 632363생성일: 2026년 10월 25일

L-Leucinol → 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide

https://huagongshe.com/reaction/632363

반응식

참여 물질

역할이름HCID투입량
반응물L-LeucinolHCID 111307—
반응물5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 71087649—
생성물5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amideHCID 71113275—

반응 단계

The title compound was synthesized in analogy to Example 280c, using 5-cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 301a) and L-leucinol (CAN 17016-87-4) as starting materials, MS (EI): m/e=361.3 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09321727B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-32f12e51eca14e1996937fca65265b93
출처 메모uspto-grants-2016_04