Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 5-Cyclopropyl-6-(2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine | HCID 43559251 | — |
| 반응물 | 5-Cyclopropyl-6-(1,1,1-trifluoropropan-2-yloxy)picolinic acid | HCID 71087435 | — |
| 생성물 | 5-Cyclopropyl-6-(2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide | HCID 71093586 | — |
반응 단계
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(1,1,1-trifluoropropan-2-yloxy)picolinic acid (Example 372 b) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials. MS (EI): m/e=399.5 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09321727B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-de2c55b460154b638a6d25d9cd53c924 |
| 출처 메모 | uspto-grants-2016_04 |