L-tert-Leucine → (2S)-2-Amino-3,3-dimethylbutanamide

HRID 6329

반응식

HRID 6329 반응식
[NH2:1][CH:2]([C:7]([NH2:9])=[O:8])[C:3]([CH3:6])([CH3:5])[CH3:4].N[C@H](C(O)=O)C(C)(C)C.N[C@@H](C(N)=O)C(C)(C)C>>[NH2:1][C@H:2]([C:7]([NH2:9])=[O:8])[C:3]([CH3:6])([CH3:5])[CH3:4]

참가 물질

4

반응물 3

HCID 164608L-tert-LeucineHCID 34964442-Amino-3,3-dimethylbutanamideHCID 10197708(2R)-2-Amino-3,3-dimethylbutanamide

생성물 1

HCID 11297986(2S)-2-Amino-3,3-dimethylbutanamide

실험 절차

In the same way as in example VIII, an incubation was carried out with DL-tertiary leucine amide. Analysis of the remaining reaction mixture after 8 hours showed that both L-tertiary leucine and D-tertiary leucine amide with an e.e. of ≥99% were present in the reaction mixture.

후처리

  1. customAnalysis of the remaining reaction mixture after 8 hours

출처 및 근거

ORD 기록
ord-ea88f85ac3924f1abb143061996c57cd
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05248608

연결된 노트

불러오는 중…