4-(Bromomethyl)benzoic acid → 4-(Bromomethyl)-N-[4-chloro-3-(2-pyridinyl)phenyl]benzamide
반응식
[Br:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=1.[Cl:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][C:14]=1[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1>>[Br:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:17][C:16]2[CH:18]=[CH:19][C:13]([Cl:12])=[C:14]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH:15]=2)=[O:9])=[CH:10][CH:11]=1참가 물질
3
실험 절차
4-(bromomethyl)benzoic acid was coupled to 4-chloro-3-(pyridin-2-yl)aniline as described in general procedure E to yield 4-(bromomethyl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide.
출처 및 근거
- ORD 기록
- ord-3ee2d98517d24648a74c4b8f2d98d649
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09321761B2
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