3-(Methanesulfonylmethyl)benzoic acid → HCID 58614934, 화합물

HRID 633159노트

반응식

HRID 633159 반응식
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[CH3:15][S:16]([CH2:19][C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](O)=[O:24])(=[O:18])=[O:17]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:23](=[O:24])[C:22]2[CH:26]=[CH:27][CH:28]=[C:20]([CH2:19][S:16]([CH3:15])(=[O:18])=[O:17])[CH:21]=2)=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

참가 물질

3

반응물 2

HCID 49625833-(Methanesulfonylmethyl)benzoic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

생성물 1

HCID 58614934HCID 58614934, 화합물

실험 절차

75 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 3-(methylsulfonylmethyl)benzoic acid via Procedure G. The crude product was purified by reverse phase HPLC to yield pure N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfonylmethyl)benzamide. MS (Q1) 401 (M)+.

후처리

  1. customThe crude product was purified by reverse phase HPLC

출처 및 근거

ORD 기록
ord-6a9a8a4d07d945a6844597c775d76ba1
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321761B2

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