Acetonitrile → 3-(4-(Cyclohexylmethoxy)pyrimidin-2-yl)-3-oxopropanenitrile

반응식

[CH:1]1([CH2:7][O:8][C:9]2[CH:14]=[CH:13][N:12]=[C:11]([C:15]([O:17]C)=O)[N:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:19][C:20]#[N:21]>>[CH:1]1([CH2:7][O:8][C:9]2[CH:14]=[CH:13][N:12]=[C:11]([C:15](=[O:17])[CH2:19][C:20]#[N:21])[N:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

참가 물질

반응물 2

HCID 6342Acetonitrile

HCID 86694671HCID 86694671, 화합물

생성물 1

HCID 866946703-(4-(Cyclohexylmethoxy)pyrimidin-2-yl)-3-oxopropanenitrile

실험 절차

CH3CN addition to methyl 4-(cyclohexylmethoxy)pyrimidine-2-carboxylate following the method described in Example 6 gives 3-(4-(cyclohexylmethoxy)pyrimidin-2-yl)-3-oxopropanenitrile.

출처 및 근거

ORD 기록: ord-6cada30eb21b4f879c49180d124dc780
출처 데이터셋: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09447078B2

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