Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Azide → 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 2-Phenoxy-2-oxo-6-iodomethyl-1,2-oxaphosphorinane | HCID 19793129 | — |
| 촉매 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 용매 | Benzene dimethylformamide | HCID 19608675 | — |
| 생성물 | 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane | HCID 19793120 | 96% |
반응 단계
A suspension containing two equivalents of sodium azide, one equivalent of the above-prepared iodonated oxaphosphorinane and a catalytic amount of about 0.1 equivalent of tetrabutylammonium bromide in benzene/DMF (1:1) was heated to 60-80 degrees C. for 16 hours to produce 2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane in 96 percent yield as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05248611 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-e5f02821feab4e68bc5f37db01f810ce |
| 출처 메모 | uspto-grants-1993_09 |