Hydrazine → 1-Amino-3-(2,2,2-trifluoroethyl)thiourea

HRID 634224노트

반응식

HRID 634224 반응식
[NH2:1][NH2:2].[F:3][C:4]([F:10])([F:9])[CH2:5][N:6]=[C:7]=[S:8]>CCO>[F:3][C:4]([F:10])([F:9])[CH2:5][NH:6][C:7]([NH:1][NH2:2])=[S:8]

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 138837771,1,1-Trifluoro-2-isothiocyanatoethane

생성물 1

HCID 337883111-Amino-3-(2,2,2-trifluoroethyl)thiourea

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Anhydrous hydrazine (0.634 mL, 20.20 mmol) (Sigma-Aldrich) was added to a stirring solution of 1,1,1-trifluoro-2-isothiocyanatoethane (2.85 g, 20.20 mmol) in EtOH (80 mL). The reaction was stirred at RT for 2 h. The solvent was removed in vacuo to give N-(2,2,2-trifluoroethyl)hydrazinecarbothioamide, and the material was used without purification.

후처리

  1. customThe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-a459b311cb304e80a6c5d8a345f664ff
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321756B2

반응 노트

불러오는 중…