Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 2-[4-(4-Benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Chloro-4,5-dihydroimidazole | HCID 236236 | — |
| 반응물 | 4-(4-Benzylaminosulfonylmethylbenzyl)-phenylamine | HCID 21876959 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 2-[4-(4-Benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline | HCID 12094388 | — |
반응 단계
A mixture of 4-(4-benzylaminosulfonylmethylbenzyl)-phenylamine (39 mg) and 2-chloro-imidazoline base (1 eq ) in 2-propanol was heated under reflux for 16 hours. A dilute solution of potassium carbonate was poured into the mixture and extracted with dichloromethane (4×15 mL). Solvents were evaported to give 2-[4-(4-benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline as a solid (41.7 mg), m.p. 115-118° C.; Analysis for C24H25CIN4O2S.H2O: Calc.: C, 58.94; H, 5.98; N, 11.46; Found: C, 59.01; H, 5.91; N, 11.30.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06184242B2 |
| 출처 데이터셋 | uspto-grants-2001_02 |
| ORD ID | ord-fd75b58aa5dc4d7084a7da2a352bbd66 |
| 출처 메모 | uspto-grants-2001_02 |