Methanol → 4-(4'-Hydroxyphenyl)-2-butanone

HRID 634888

반응식

HRID 634888 반응식
C[C:2]1[C@@H:19](OC([C@H](O)[C@@H](NC(C2C=CC=CC=2)=O)C2C=CC=CC=2)=O)[CH2:18][C@:14]2(O)[C:15](C)(C)[C:3]=1[C@@H](OC(C)=O)C([C@@]1(C)[C@H:12]([C@@H:13]2OC(C2C=CC=CC=2)=O)[C@:11]2([O:53]C(C)=O)CO[C@@H:10]2C[C@@H]1O)=O.C[OH:64]>>[CH3:10][C:11]([CH2:12][CH2:13][C:14]1[CH:18]=[CH:19][C:2]([OH:64])=[CH:3][CH:15]=1)=[O:53]

참가 물질

3

반응물 2

HCID 887MethanolHCID 36314Paclitaxel

생성물 1

HCID 216484-(4'-Hydroxyphenyl)-2-butanone

실험 절차

Taxus wallichiana known as the Himalayan yew is available in India. The applicants have investigating the different parts of this plant from different Himalayan regions of India for isolation of naturally occurring analogues of taxol, its important precursors and other biologically active compounds. During the course of investigation the applicants have isolated 2 compounds of 4-aryl-2-butanol namely betuligenol having formula C10H14O2, mp 69-70° C., [α]n+20 (C1, MeOH) and betuliloside having formula C16H24O7 mp 187-188°, [α]n+22° (C1, MeOH) from the leaves of T. wallichiana.

출처 및 근거

ORD 기록
ord-155f7e0dea044e9eaeba54feb561dae2
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06184367B2

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