1-Heptene → 2-(2-n-Propoxy-5-Morpholinosulfonylphenyl)-8-(1-Hepten-1-yl)Quinazolin-4(3H)-One

HRID 635203

반응식

HRID 635203 반응식
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:13])=[O:12])=[CH:7][C:6]=1[C:20]1[NH:29][C:28](=[O:30])[C:27]2[C:22](=[C:23](Br)[CH:24]=[CH:25][CH:26]=2)[N:21]=1)[CH2:2][CH3:3].[CH2:32]=[CH:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]>>[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:13])=[O:12])=[CH:7][C:6]=1[C:20]1[NH:29][C:28](=[O:30])[C:27]2[C:22](=[C:23]([CH:32]=[CH:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH:24]=[CH:25][CH:26]=2)[N:21]=1)[CH2:2][CH3:3]

참가 물질

3

반응물 2

HCID 116101-HepteneHCID 1361864092-(2-n-propoxy-5-morpholinosulfonylphenyl)-8-bromoquinazolin-4(3H)-one

생성물 1

HCID 1360413722-(2-n-Propoxy-5-Morpholinosulfonylphenyl)-8-(1-Hepten-1-yl)Quinazolin-4(3H)-One수율 53.2%

실험 절차

The title compound is prepared analogously to the method of Example 1, starting with 2-(2-n-propoxy-5-morpholinosulfonylphenyl)-8-bromoquinazolin-4(3H)-one and 1-heptene.

출처 및 근거

ORD 기록
ord-36f6c2358b8b4e43b2e3adab177400ea
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187779B1

연결된 노트

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