Cycloheptanone Oxime → 3-(3-(4-(3-chlorophenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole

HRID 635274

반응식

HRID 635274 반응식
[C:1]1(=[N:8][OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]2[CH2:22][CH2:21][N:20]([CH2:23][CH2:24][CH2:25][C:26](OCC)=O)[CH2:19][CH2:18]2)[CH:14]=[CH:15][CH:16]=1>>[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]2[CH2:22][CH2:21][N:20]([CH2:23][CH2:24][CH2:25][C:26]3[O:9][N:8]=[C:1]4[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]=34)[CH2:19][CH2:18]2)[CH:14]=[CH:15][CH:16]=1

참가 물질

3

반응물 2

HCID 137457Cycloheptanone OximeHCID 17773229Ethyl 4-(4-(3-chlorophenyl)piperidin-1-yl)-n-butyrate

생성물 1

HCID 599394283-(3-(4-(3-chlorophenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole

실험 절차

By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(3-chlorophenyl)piperidin-1-yl)-n-butyrate, 3-(3-(4-(3-chlorophenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.

출처 및 근거

ORD 기록
ord-ab38c654cce641c39fa42e7fa47ad72c
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187774B1

연결된 노트

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