Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 635478노트

반응식

HRID 635478 반응식
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

참가 물질

3

반응물 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772, 화합물

생성물 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

실험 절차

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

후처리

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

출처 및 근거

ORD 기록
ord-3d73f6e20225411fb67d8301ad89e7e7
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187821B1

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