Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Chloro-4-fluorobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 3'-Chloro-4'-fluoroacetophenone | HCID 520422 | — |
| 반응물 | Sodium Bisulfite | HCID 23665763 | — |
| 반응물 | Sodium hypobromite | HCID 23673712 | — |
| 생성물 | 3-Chloro-4-fluorobenzoic acid | HCID 520989 | 74% |
반응 단계
The 3-chloro-4-fluoroacetophenone is then reacted with an aqueous solution of sodium hypobromite, the aqeuous phase is treated with sodium hydrogensulfite and acidified with hydrochloric acid, and the precipitated product is recrystallized from benzene. 3-Chloro-4-fluorobenzoic acid obtained in a yield of 74%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06187952B1 |
| 출처 데이터셋 | uspto-grants-2001_02 |
| ORD ID | ord-d546c0be93c5496da77831fb43df7de5 |
| 출처 메모 | uspto-grants-2001_02 |