4-Fluorobenzaldehyde → 4-Fluorobenzoyl chloride

HRID 635546

반응식

HRID 635546 반응식
Cl[C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([Cl:7])=[O:6].FC1C=CC(C=O)=CC=1>>[F:11][C:10]1[CH:9]=[CH:8][C:4]([C:5]([Cl:7])=[O:6])=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 680234-FluorobenzaldehydeHCID 27365483-Chloro-4-fluorobenzoyl Chloride

생성물 1

HCID 678794-Fluorobenzoyl chloride

실험 절차

A process for the preparation of 3-chloro-4-fluorobenzoyl chloride, which comprises reacting 4-fluorobenzaldehyde with a chlorinating agent in the presence of a free-radical initiator in the presence or absence of a solvent at from −20 to 200° C. to give 4-fluorobenzoyl chloride, and reacting the 4-fluorobenzoyl chloride with a chlorinating agent in the presence of a chlorination catalyst in the presence or absence of a solvent at from −20 to 200° C. to give 3-chloro-4-fluorobenzoyl chloride.

후처리

  1. customat from −20 to 200° C.

출처 및 근거

ORD 기록
ord-e1e64f458c8e435a9fe9e371e1367bb0
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187952B1

연결된 노트

불러오는 중…