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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 635923생성일: 2026년 10월 25일

5-Azaindole → 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole

https://huagongshe.com/reaction/635923

반응식

참여 물질

역할이름HCID투입량
반응물5-AzaindoleHCID 9220—
반응물PyrrolidineHCID 31268—
용매EthanolHCID 702—
생성물3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-AzaindoleHCID 10130974102.9%

반응 단계

A mixture of 5-azaindole (0.5 g, 4.23 mmol), 1,2,3,5,6,8,8a-heptahydrohydro-7-oxo-indolizine (589 mg, 4.23 mmol) and pyrrolidine (3.0 g, 42.3 mmol) in ethanol (4 mL) were heated to reflux for 6 hrs. The reaction mixture was cooled, filtered, and the collected solid washed with ether to give 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole (0.521 g, 51.6%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06191141B1
출처 데이터셋uspto-grants-2001_02
ORD IDord-feab868e0f7f4ebfb97ce1a038163ae6
출처 메모uspto-grants-2001_02