Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → p-Cyclohexylbenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | 18-Crown-6 | HCID 28557 | — |
| 반응물 | (4-Cyclohexylphenyl)methanol | HCID 22492024 | — |
| 반응물 | HCID 178418287 | HCID 178418287 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | p-Cyclohexylbenzaldehyde | HCID 119689 | — |
반응 단계
18-Crown-6 (Aldrich; 4 molar eq.) and pyridinium chlorochromate (Aldrich; 4 molar eq.) were added together in chloroform and stirred for 20 minutes. 4-Cyclohexylbenzylalcohol (from Example D22 below; 1 molar eq.) was added and stirring continued for 3 hours. Ether was added and the mixture filtered through a plug of silica eluting with ether. The solvent was removed via rotary evaporation. The residue was dissolved in ether and washed with water. The organic layer was dried over Na2SO4, filtered, and concentrated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06191166B1 |
| 출처 데이터셋 | uspto-grants-2001_02 |
| ORD ID | ord-ad55b80dab7b4b94806b68929f69acf1 |
| 출처 메모 | uspto-grants-2001_02 |