1,4-Dioxane hydrochloride → HCID 54539135, 화합물

반응식

C([N:8]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[N:12]=1)[CH2:9][CH3:10])(OC(C)(C)C)=O.Cl.O1CCOCC1>>[CH2:9]([NH:8][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[N:12]=1)[CH3:10]

참가 물질

반응물 2

HCID 204431481,4-Dioxane hydrochloride

HCID 21257558HCID 21257558, 화합물

생성물 1

HCID 54539135HCID 54539135, 화합물

실험 절차

A solution of ethyl 2-(N-Boc-N-ethylamino)-6-pyridylacetate (1.5 g, 4.87 mmol) and 4M HCl/dioxane (5 mL, 20 mol) was stirred at RT overnight, then was concentrated. Reconcentration from toluene gave the title compound as white solid: MS (ES) m/e 209 (M+H)+.

후처리

concentrationwas concentrated

출처 및 근거

ORD 기록: ord-6e4cfb451cba429b8fe195d1437e8634
출처 데이터셋: uspto-grants-2001_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06191304B1

반응 노트

불러오는 중…