Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl butylmalonate → Phytanic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl butylmalonate | HCID 67244 | — |
| 반응물 | Diethyl 2-benzylpropanedioate | HCID 69090 | — |
| 반응물 | Decanoic acid, 2-methyl- | HCID 91167 | — |
| 반응물 | Phytol | HCID 5280435 | — |
| 반응물 | 2-Butyldodecanoic acid | HCID 12424127 | — |
| 반응물 | 2,2-Dibutyldodecanoic acid | HCID 19087895 | — |
| 촉매 | chromium (VI) trioxide | HCID 10219390 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Phytanic Acid | HCID 26840 | — |
반응 단계
The 2-benzylalkanoic and 2-butylalkanoic acids were prepared by the malonic ester method starting from diethyl benzylmalonate or diethyl butylmalonate and the appropriate alkyl bromide. The procedure used was analogous to that for the preparation of 2-methyldecanoic acid. Preparation of 2,2-dibutyldodecanoic acid was accomplished by alkylation of 2-butyldodecanoic acid using the method of Pfeffer, Silbert, and Chirinko. Hydrogenation of phytol followed by oxidation of the resulting saturated alcohol with a solution of chromium trioxide in acetic acid gave 3,7,11,15-tetramethylhexadecanoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04556495 |
| 출처 데이터셋 | uspto-grants-1985_12 |
| ORD ID | ord-7c1a0b002e334083948a27da8d74ec1b |
| 출처 메모 | uspto-grants-1985_12 |