2,4,5-Trimethylimidazole → 1,3-Dihydro-4-methyl-5-[4-(2,4,5-trimethyl-1H-imidazol-1-yl)benzoyl]-2H-imidazol-2-one

반응식

F[C:2]1[CH:16]=[CH:15][C:5]([C:6]([C:8]2[NH:9][C:10](=[O:14])[NH:11][C:12]=2[CH3:13])=[O:7])=[CH:4][CH:3]=1.[CH3:17][C:18]1[NH:19][C:20]([CH3:24])=[C:21]([CH3:23])[N:22]=1>>[CH3:13][C:12]1[NH:11][C:10](=[O:14])[NH:9][C:8]=1[C:6](=[O:7])[C:5]1[CH:15]=[CH:16][C:2]([N:19]2[C:20]([CH3:24])=[C:21]([CH3:23])[N:22]=[C:18]2[CH3:17])=[CH:3][CH:4]=1

참가 물질

반응물 2

HCID 699762,4,5-Trimethylimidazole

HCID 155675394-(4-Fluorobenzoyl)-5-methyl-1,3-dihydro-2H-imidazol-2-one

생성물 1

HCID 138159761,3-Dihydro-4-methyl-5-[4-(2,4,5-trimethyl-1H-imidazol-1-yl)benzoyl]-2H-imidazol-2-one

실험 절차

In a manner similar to Example IV react 4-(4-fluorobenzoyl)-1,3-dihydro-5-methyl-2H-imidazol-2-one with 2,4,5-trimethyl-1H-imidazole to produce the title compound.

출처 및 근거

ORD 기록: ord-075d3dfbdf574812a50dc385e2f18dca
출처 데이터셋: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04556665

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