4-(2-methyl-1H-imidazol-1-yl)benzoic acid → CK 2130

반응식

[CH2:1]([C:3]1[NH:7][C:6](=[O:8])[NH:5][C:4]=1[C:9]([OH:11])=O)[CH3:2].[CH3:12][C:13]1[N:14]([C:18]2[CH:26]=[CH:25][C:21](C(O)=O)=[CH:20][CH:19]=2)[CH:15]=[CH:16][N:17]=1>>[CH2:1]([C:3]1[NH:7][C:6](=[O:8])[NH:5][C:4]=1[C:9](=[O:11])[C:21]1[CH:25]=[CH:26][C:18]([N:14]2[CH:15]=[CH:16][N:17]=[C:13]2[CH3:12])=[CH:19][CH:20]=1)[CH3:2]

참가 물질

반응물 2

HCID 138159884-(2-methyl-1H-imidazol-1-yl)benzoic acid

HCID 138159895-Ethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid

생성물 1

HCID 127770CK 2130

실험 절차

In a manner similar to Example I react 2,3-dihydro-5-ethyl-2-oxo-1H-imidazole-4-carboxylic acid with 4-(2-methyl-1H-imidazol-1-yl)benzoic acid to produce the title compound.

출처 및 근거

ORD 기록: ord-c350033f51124c60a64fd6377684dfc2
출처 데이터셋: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04556665

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