Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylamine → 1-(4-Bromobutyl)cyclopentanecarboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylamine | HCID 7912 | — |
| 반응물 | 1,4-Dibromobutane | HCID 8056 | — |
| 반응물 | Methyl cyclopentanecarboxylate | HCID 78365 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | 1-(4-Bromobutyl)cyclopentanecarboxylic acid methyl ester | HCID 22954343 | — |
반응 단계
The title compound was prepared using a similar procedure as described in Example 1, Step 1, starting from diisopropylamine (21 mL, 150 mmol), n-butyllithium (58 mL, 145 mmol), cyclopentanecarboxylic acid methyl ester (13.1 g, 100 mmol), and 1,4-dibromobutane (21.59 g, 100 mmol), and after distillation, resulted in a colorless oil (12.8 g, 48%). ES(+)-HRMS m/e calcd. for C11H19BrO2 (M+H)+ 262.0568, obsd. 262.0565.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447035B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-08af6405ee1145fda3d257da68d88168 |
| 출처 메모 | uspto-grants-2016_09 |