Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → Methyl acetate hexane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | 2-Nitrobenzenesulfonamide | HCID 138510 | — |
| 반응물 | Dipropan-2-yl (aminomethyl)phosphonate | HCID 13740526 | — |
| 생성물 | Methyl acetate hexane | HCID 23449302 | — |
반응 단계
10 g (0.58 mole) of 2-nitrophenylsulfonamide are suspended in 20 ml of toluene and heated to reflux temperature. 17.0 g (0.087 mole) of diisopropyl aminomethylphosphonate are added dropwise to the hot solution. The reaction mixture is then boiled under reflux for 10 hours, cooled and evaporated. Chromatographing the residue over silica gel with a 4:1 methyl acetate/hexane mixture gives 1.6 g of 2-(di-i-propoxyphosphonylmethylamino)-phenylsulfonamide in the form of a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04559078 |
| 출처 데이터셋 | uspto-grants-1985_12 |
| ORD ID | ord-bbda92106ec645718dfb8917382af9a0 |
| 출처 메모 | uspto-grants-1985_12 |