Ethyl 3-(6-methylpyridin-3-yl)prop-2-enoate → Ethyl 3-(6-methyl-3-pyridyl)propionate
반응식
[CH2:1]([O:3][C:4](=[O:14])[CH:5]=[CH:6][C:7]1[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=1)[CH3:2]>C(O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][CH2:6][C:7]1[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=1)[CH3:2]참가 물질
4
실험 절차
17.8 g (0.092 mole) of 3-(6-methyl-3-pyridyl)-acrylic acid ethyl ester in 100 ml of ethanol are hydrogenated at 40° C./atmospheric pressure in the presence of 1.0 g of palladium/active carbon (10% Pd). On completion of the reaction, the reaction mixture is filtered and the solvent is concentrated in vacuo, leaving 16.2 g (90%) of a colorless oil.
후처리
- customare hydrogenated at 40° C.
- customOn completion of the reaction
- filtrationthe reaction mixture is filtered
- concentrationthe solvent is concentrated in vacuo
출처 및 근거
- ORD 기록
- ord-ddf2b9c231d74c109bfe921aaa393aa9
- 출처 데이터셋
- uspto-grants-1985_12
- 특허 번호
- US04559344
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