Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydroquinone → 3,4-Dihydro-2H-1-benzopyran-6-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydroquinone | HCID 785 | — |
| 반응물 | Isophytol | HCID 10453 | — |
| 반응물 | Sodium Dithionite | HCID 24489 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 생성물 | 3,4-Dihydro-2H-1-benzopyran-6-ol | HCID 15122338 | — |
반응 단계
2,6-dimethylquinone 111 is reduced with sodium dithionite to the hydroquinone 112, which is then reacted with 3,7,11,15-tetramethyl-3-hydroxy-1-hexadecene 113 and ZnCl2 to form the 6-chromanol 114. Conversion to the protected intermediate 115 is followed by bromination with Br2 and silver trifluoroacetate to form the bromide 116. Finally, 116 can be deprotected and oxidized with ceric ammonium nitrate (CAN) to yield 117.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447006B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-a4c73b0460b94898a0a84e03a3b86891 |
| 출처 메모 | uspto-grants-2016_09 |