참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | N-Acetyl-L-leucine | HCID 70912 | — |
| 반응물 | N-Acetylisoleucine | HCID 7036275 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | L-Leucine | HCID 6106 | — |
반응 단계
86.6 grams of this mixture of equal parts of N-acetyl-leucine and N-acetyl-isoleucine were suspended in 400 ml of water and adjusted to pH 7.0 with 50% aqueous sodium hydroxide. There were added 50 mg of CoCl2X6H2O and 50 mg of commerical pig kidney acylase (1200 U/mg) and the mixture was filled up to 500 ml with water. The clear solution was stirred at 36° C. for 6 hours. By filtering with suction, washing and drying there were obtained 17.9 grams of pure L-leucine having a rotary value of [α]D25 =+15.9°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04562153 |
|---|
| 출처 데이터셋 | uspto-grants-1985_12 |
|---|
| ORD ID | ord-1d3a85980dba4ee1a0ce9052fe130086 |
|---|
| 출처 메모 | uspto-grants-1985_12 |
|---|
